Pharma moves fast.

Pharma moves fast.

Your supply chain needs to move faster.

Continuous product launches, increasingly rapid replacement cycles, and more than 500,000 potential SKUs. In a market where traditional replenishment processes are no longer adequate, simply reordering what is missing is not enough.You need to anticipate what will be needed - before the market asks for it.

Assortment decisions can no longer rely on the past

Decision models based exclusively on historical data are no longer sufficient. Today it is necessary to:

01

Ensure assortment continuity

in a market where thousands of references change every year

02

Anticipate real warehouse demand

identifying required products before they become critical shortages

03

Reorder the right quantity at the right time

without tying up capital or losing sales

04

Manage complex procurement and dynamic pricing

through data-driven decisions, not reactive ones

What can be done?

Apply the principles of effective supply chain management in a measurable and structured way.

Most pharmaceutical wholesalers have not yet calculated what unengineered supply chain decisions truly cost them. Profiter’s implementation data consistently shows that the recoverable value represents up to one third of first-margin improvement potential, invisible today because it has never been measured.

In this context, Profiter has supported leading groups such as PHOENIX Pharma, delivering tangible improvements in forecasting, service levels, and margins across the entire supply chain.

Ensuring assortment continuity

High SKU turnover makes assortment continuity a structural challenge. This is driven by the constant introduction of:

Direct substitutes

New versions that completely replace a previous code.

Equivalents

Same function or active ingredient, different commercial positioning.

Related products

Nomenclature or data-structure relationships not always recognised by ERP systems.

If not updated in real time, the assortment quickly becomes outdated. And with it, your ability to respond to demand. You need a catalogue that synchronises with the market in real time — not afterwards.

Determining what truly belongs in your assortment

Traditional processes rely on what is already in stock.
This approach becomes problematic, especially with high turnover and new product launches:

pharmacies query digital catalogues to request products:
if a new product is not available, it is simply not requested

as a result, visibility on “missing demand” is lost and the catalogue becomes misaligned with the market

If a product is not visible in pharmacies’ digital systems, it does not exist in their orders. You need a tool that identifies which SKUs should be available, not only those already in stock

Missing demandnever recordedPHARMACY REQUESTSearch in the digital catalogueIN STOCK?Found or not foundORDER PLACEDOnly visible SKUs are orderedDEMAND DATAThe cycle repeats, blindly

Reordering the right quantity at the right time

Once you define what to stock, the next step is understanding when and how much to order. Effective dynamic replenishment means inventory decisions must be demand-driven. Getting them wrong is costly.

Overstock / Excess inventory

Direct costs, expiry risk, slower rotation, ESG inefficiencies

Shortage / Stockouts

Lost sales, allocations, dissatisfied customers, service disruptions.

Two opposite extremes that lead to the same result: eroded margins and weakened service levels. Without an effective predictive system, oscillating between excess and shortage is inevitable — and always expensive.

Managing complex procurement and dynamic pricing

Several factors make procurement and pricing increasingly complex.

01 · MARKET VOLATILITY

The end of static price lists

Frequent changes, prices linked to availability and demand.

02 · NEGOTIATION

Complex purchasing conditions

Bundles, volume thresholds, variable conditions — a real jungle for buyers.

03 · RISK MANAGEMENT

Growing uncertainty

Uncertain lead times, uneven supplier reliability, dynamic planning needs.

04 · DOWNSTREAM MARGIN

Competitive pricing toward pharmacies

Sustainable margins and real-time availability are now critical.

Determining the “right price” is now a data-driven exercise, not an administrative one. And those who control pricing, control the market.

Evolving without disruption

The idea is simple: enhance wholesalers’ operations without changing their IT architecture. An innovation that respects established Just-in-Time (JIT) principles while overcoming the limits of traditional processes through granular forecasting.

How it works

01

Start from demand forecasting

Not from current availability. Not from historical data. Anticipate what the market will ask for, before it does.

02

Forecast defines procurement needs

Demand signals determine what needs to be purchased.

03

Demand is fulfilled more accurately

Reducing extra costs and improving margins.

Realistic forecast = assortment → sales forecast → procurement → sales → margins

CURIO: the first AI that speaks the language of pharma

Predictive precision

Generates SKU-level forecasts through demand sensing, integrating relevant endogenous and exogenous data (internal data, industry signals, seasonal patterns, trends, competitors).

Decision speed

Continuous updates on availability, costs, and demand

Vertical intelligence

Recognises direct substitutes, equivalents, regulatory impacts, and sector-specific dynamics.

Just In Time, enhanced by predictive AI

Profiter applies Just-in-Time (JIT) principles to pharmaceutical distribution, ensuring availability and service levels while minimizing capital tied up across the entire operational flow.
This is achieved through AI-driven monitoring of operational KPIs.

Availability under control

Backorder Rate

Stock coverage based on forecasted consumption

Order fulfillment continuity

Service level measurement

On Time In Full (OTIF)

Picking accuracy

Delivery punctuality

Delivery Quality

Capital
optimisation

Inventory turnover

Inventory Accuracy Gap (IAG) for physical vs accounting alignment

Inventory Discrepancy Indicator (IDI) to reduce value discrepancies

Inventory Discrepancy Management (IDM) to control inventory adjustments

The KPIs that turn JIT into a competitive advantage

Beyond operational KPIs, Profiter uses AI-driven Trade Performance Indicators (TPI) to evaluate purchasing opportunities by integrating financial, logistical, and risk management factors.

COI

Cost Opportunity Index (COI)

measures the real convenience of a purchase per day of coverage generated.

CDI

Cost of Dead Inventory (CDI)

highlights the hidden cost of overstock by integrating capital, time in stock, and devaluation risk.

ORI

Obsolescence Risk Index (ORI)

estimates the risk of stock losing value before being sold, considering lifecycle, substitutes, and price dynamics.

CURIO optimises pharmaceutical supply chains: the PHOENIX Pharma case

A collaboration that turned forecasting into a concrete lever of competitiveness.

forecast accuracy

+0%

Measurable lift in forecasting accuracy versus the internal baseline.

logistics costs

-0.0%

Average reduction across the operational flow.

margin improvement

+0%

Direct margin improvement.

estimated annual savings

0

Estimated annual savings on a 28,000 SKU base

THE CUSTOMER

A leading European pharmaceutical distribution group

49.000+ employees, operating across 29 markets. Dual leadership in wholesale and retail in Southern Europe

The Challenge

Forecasting demand in a complex market

Pharma distribution requires precise forecasts to avoid shortages, overstock, and uncontrolled costs. PHOENIX aimed to objectively assess how much AI could improve accuracy compared to its internal forecasting system.

The approach

Benchmark on ~ 1.000 SKUs ● Profiter AI model vs. internal forecast ● Measurement via Wmape, logistics KPIs, and cost analysis

Results after 12 months

64% of cases: more accurate forecasts ● 7,9% average reduction in logistics costs ● 911.000 € estimated annual savings (on a 28,000 SKU base)

Value delivered to PHOENIX

Higher product availability ● More robust purchasing decisions ● Increased negotiation power with suppliers ● Direct impact on margins and service levels

CURIO optimises pharmaceutical supply chains: the PHOENIX Pharma case

A collaboration that turned forecasting into a concrete lever of competitiveness.

forecast accuracy

+0%

Measurable lift in forecasting accuracy versus the internal baseline.

logistics costs

-0.0%

Average reduction across the operational flow.

margin improvement

+0%

Direct margin improvement.

estimated annual savings

0

Estimated annual savings on a 28,000 SKU base

THE CUSTOMER

A leading European pharmaceutical distribution group

49.000+ employees, operating across 29 markets. Dual leadership in wholesale and retail in Southern Europe

The Challenge

Forecasting demand in a complex market

Pharma distribution requires precise forecasts to avoid shortages, overstock, and uncontrolled costs. PHOENIX aimed to objectively assess how much AI could improve accuracy compared to its internal forecasting system.

The approach

Benchmark on ~ 1.000 SKUs ● Profiter AI model vs. internal forecast ● Measurement via Wmape, logistics KPIs, and cost analysis

Results after 12 months

64% of cases: more accurate forecasts ● 7,9% average reduction in logistics costs ● 911.000 € estimated annual savings (on a 28,000 SKU base)

Value delivered to PHOENIX

Higher product availability ● More robust purchasing decisions ● Increased negotiation power with suppliers ● Direct impact on margins and service levels

CURIO optimises pharmaceutical supply chains: the PHOENIX Pharma case

A collaboration that turned forecasting into a concrete lever of competitiveness.

forecast accuracy

+0%

Measurable lift in forecasting accuracy versus the internal baseline.

logistics costs

-0.0%

Average reduction across the operational flow.

margin improvement

+0%

Direct margin improvement.

estimated annual savings

0

Estimated annual savings on a 28,000 SKU base

THE CUSTOMER

A leading European pharmaceutical distribution group

49.000+ employees, operating across 29 markets. Dual leadership in wholesale and retail in Southern Europe

The Challenge

Forecasting demand in a complex market

Pharma distribution requires precise forecasts to avoid shortages, overstock, and uncontrolled costs. PHOENIX aimed to objectively assess how much AI could improve accuracy compared to its internal forecasting system.

The approach

Benchmark on ~ 1.000 SKUs ● Profiter AI model vs. internal forecast ● Measurement via Wmape, logistics KPIs, and cost analysis

Results after 12 months

64% of cases: more accurate forecasts ● 7,9% average reduction in logistics costs ● 911.000 € estimated annual savings (on a 28,000 SKU base)

Value delivered to PHOENIX

Higher product availability ● More robust purchasing decisions ● Increased negotiation power with suppliers ● Direct impact on margins and service levels

Turn complex data into faster, more profitable operational decisions.

Anticipate demand. Optimise inventory. Strengthen margins and competitiveness.